BDBM50551961 CHEMBL4791199

SMILES CC(C)(C)OC(=O)N1CC[C@]2([C@@H]1c1cccc(c1)-c1ccccc1)C(=O)Nc1ccccc21

InChI Key InChIKey=HNKXJPOYCMLZTF-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50551961   

TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50551961(CHEMBL4791199)
Affinity DataEC50:  0.843nMAssay Description:Agonist activity at human RXRalpha/LXRalpha expressed in HEK293 cells measured after 20 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50551961(CHEMBL4791199)
Affinity DataEC50:  0.632nMAssay Description:Agonist activity at human RXRalpha/LXRbeta expressed in HEK293 cells measured after 20 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50551961(CHEMBL4791199)
Affinity DataKi:  600nMAssay Description:Displacement of hyodeoxycholicacid-based fluorescent tracer from recombinant human LXRbeta LBD (215 to 461 residues) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed