BDBM50551914 CHEMBL4742730

SMILES Cn1c(cc2cc(F)ccc12)C(=O)Nc1cccc2CCCN(Cc3ccc(OC4CCNCC4)cc3)c12

InChI Key InChIKey=XXKLVTNJHLONBN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551914   

TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50551914(CHEMBL4742730)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human recombinant LSD1 using fluorogenic ADHP based substrate preincubated for 30 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50551914(CHEMBL4742730)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human MAOA expressed in baculovirus infected Sf9 insect cells using luminogenic MAO substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50551914(CHEMBL4742730)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human MAOB expressed in baculovirus infected Sf9 insect cells using luminogenic MAO substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50551914(CHEMBL4742730)
Affinity DataIC50: 540nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed