BDBM50551616 CHEMBL1512476

SMILES Oc1ccccc1C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=XBPYTDZHCNJRBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551616   

TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551616(CHEMBL1512476)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551616(CHEMBL1512476)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551616(CHEMBL1512476)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition and measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50551616(CHEMBL1512476)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Sirtuin-1 (unknown origin) incubated for 30 mins by luminogenic SIRT-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed