BDBM50551604 CHEMBL4749004

SMILES Oc1cc2ccccc2cc1C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=PMBBIXLWMMOUGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50551604   

TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551604(CHEMBL4749004)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551604(CHEMBL4749004)
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50551604(CHEMBL4749004)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Sirtuin-1 (unknown origin) incubated for 30 mins by luminogenic SIRT-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed