BDBM50551597 CHEMBL4753700

SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(CCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)CC1

InChI Key InChIKey=CBWIPIZLLNOTMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551597   

TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50551597(CHEMBL4753700)
Affinity DataIC50: 19nMAssay Description:Inhibition of EGFR L858R/T790M (unknown origin) using Poly (Glu, Tyr) 4:1 as substrate measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50551597(CHEMBL4753700)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Poly (Glu, Tyr) 4:1 as substrate measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed