BDBM50551591 CHEMBL4784145

SMILES [#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#7]-[#6](=O)\[#6]=[#6]\c2ccc(cc2)-[#6](=[#6]-2/[#6]-[#6]-[#6]-[#6]-[#6]-2)\c2ccc(-[#8])cc2)cc1

InChI Key InChIKey=ACDNOMQBUVEDQT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551591   

TargetEstrogen receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551591(CHEMBL4784145)
Affinity DataIC50: 6.40nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551591(CHEMBL4784145)
Affinity DataIC50: 28nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551591(CHEMBL4784145)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551591(CHEMBL4784145)
Affinity DataIC50: 216nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed