BDBM50551529 CHEMBL4785863

SMILES COC[C@H](NC(=O)[C@H](CC(=O)NCC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1)C(=O)N[C@@H](CC(C)C)C(=O)c1ccco1

InChI Key InChIKey=SRRHMJFNPOAJHK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551529   

TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50551529(CHEMBL4785863)
Affinity DataIC50: 180nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50551529(CHEMBL4785863)
Affinity DataKd:  4.80E+3nMAssay Description:Binding affinity to immobilized human 20S proteasome beta 5 subunit by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed