BDBM50551228 CHEMBL4749731

SMILES CC(C)c1cc(C(=O)N2Cc3ccc(NC(=O)CCC(=O)NO)cc3C2)c(O)cc1O

InChI Key InChIKey=HWHOXINBNOJDGW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551228   

TargetHeat shock protein HSP 90-alpha(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50551228(CHEMBL4749731)
Affinity DataIC50: 123nMAssay Description:Inhibition of HSP90a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50551228(CHEMBL4749731)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using fluorescence substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50551228(CHEMBL4749731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50551228(CHEMBL4749731)
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of recombinant human HDAC8 using RHK-K(Ac)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed