BDBM50551214 CHEMBL4790145

SMILES COc1ccc2nc(nc(CCNC(C)=O)c2c1)C1CC1

InChI Key InChIKey=OBBXEJIBJWTYKK-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551214   

TargetMelatonin receptor type 1A(Human)
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50551214(CHEMBL4790145)
Affinity DataEC50:  429nMAssay Description:Agonist activity at human MT1 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50551214(CHEMBL4790145)
Affinity DataEC50:  238nMAssay Description:Agonist activity at human MT2 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50551214(CHEMBL4790145)
Affinity DataKi:  22nMAssay Description:Displacement of 2-[125l]-lodomelatonin from human MT1 expressed in CHO cells incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50551214(CHEMBL4790145)
Affinity DataKi:  26nMAssay Description:Displacement of 2-[125l]-lodomelatonin from human MT2 expressed in CHO cells incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed