BDBM50551152 CHEMBL4750230

SMILES CS(=O)(=O)N1CCC[C@H]1CNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=SXEJGTMLSPHRPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551152   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551152(CHEMBL4750230)
Affinity DataIC50: 186nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in N-formylkynurenine production incubated for 12 hrs by microplate reader ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551152(CHEMBL4750230)
Affinity DataIC50: 717nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 30 mins by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed