BDBM50551148 CHEMBL4783332

SMILES NS(=O)(=O)N1CC[C@@H](CNc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)C1

InChI Key InChIKey=PTMVAXIURPPRBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551148   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551148(CHEMBL4783332)
Affinity DataIC50: 20nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in N-formylkynurenine production incubated for 12 hrs by microplate reader ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551148(CHEMBL4783332)
Affinity DataIC50: 109nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 30 mins by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed