BDBM50550743 CHEMBL4764463

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)c4nnc(o4)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key InChIKey=IRBBFXPKIBQFKT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50550743   

TargetTyrosine-protein kinase receptor UFO(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal GST-fused Axl cytoplasmic domain (464 to 885 residues) expressed in baculovirus expression system using CSKtide as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 71nMAssay Description:Inhibition of human N-terminal GST-fused c-MET cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression system using Srctide as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 81nMAssay Description:Inhibition of human N-terminal GST-fused KDR cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using CSKtide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 63nMAssay Description:Inhibition of human N-terminal GST-tagged c-Kit cytoplasmic domain (544 to end residues) expressed in baculovirus infected Sf21 insect cells using pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 103nMAssay Description:Inhibition of human N-terminal GST-fused FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system using Srctide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 200nMAssay Description:Inhibition of human His-tagged PDGFRB cytoplasmic domain expressed in baculovirus expression system using peptide substrate measured after 1 hr by mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 200nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550743(CHEMBL4764463)
Affinity DataIC50: 200nMAssay Description:Inhibition of Tyro3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed