BDBM50550739 CHEMBL4788683

SMILES [O-][N+](=O)c1ccc(NC(=O)C(N(C(=O)c2ccc(cc2)C(F)(F)F)c2ccccc2)c2ccc(cc2)[N+]([O-])=O)cc1

InChI Key InChIKey=GDBNAEMVDGQOCE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50550739   

TargetMatrix metalloproteinase-9(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50550739(CHEMBL4788683)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of MMP-9 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50550739(CHEMBL4788683)
Affinity DataIC50: 139nMAssay Description:Inhibition of MMP-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50550739(CHEMBL4788683)
Affinity DataIC50: 41nMAssay Description:Inhibition of MMP-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50550739(CHEMBL4788683)
Affinity DataIC50: 113nMAssay Description:Inhibition of MMP-13 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50550739(CHEMBL4788683)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed