BDBM50550677 CHEMBL4788818

SMILES CN1CC[C@H](C1)Oc1ccc2Sc3c(Cc2c1)cccc3-c1cc(=O)cc(o1)N1CCOCC1

InChI Key InChIKey=BLMRFUXYKIGLND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550677   

TargetSerine-protein kinase ATM(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550677(CHEMBL4788818)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550677(CHEMBL4788818)
Affinity DataIC50: 100nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed