BDBM50550664 CHEMBL4791332

SMILES CC(C)(O)C1CCN(CCOc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)CC1

InChI Key InChIKey=CVCGZRHVSJZEIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550664   

TargetSerine-protein kinase ATM(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550664(CHEMBL4791332)
Affinity DataIC50: 860nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50550664(CHEMBL4791332)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed