BDBM50550642 CHEMBL4787081

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)NCC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1)B(O)O

InChI Key InChIKey=DPFMPSWJJIWBOL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50550642   

TargetProteasome subunit beta type-1(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550642(CHEMBL4787081)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550642(CHEMBL4787081)
Affinity DataIC50: 440nMAssay Description:Inhibition of human 20S constitutive proteasome beta 2 subunit trypsin-like activity using fluorogenic peptide Ac-WLR-AMC as substrate in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550642(CHEMBL4787081)
Affinity DataIC50: 9nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550642(CHEMBL4787081)
Affinity DataIC50: 29nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550642(CHEMBL4787081)
Affinity DataIC50: 130nMAssay Description:Inhibition of human 20S immunoproteasome beta 2 subunit trypsin-like activity using fluorogenic peptide Ac-WLR-AMC as substrate in presence of PA28al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550642(CHEMBL4787081)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed