BDBM50550641 CHEMBL4781914

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O)B(O)O

InChI Key InChIKey=QZBBJKHZODGFHC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50550641   

TargetProteasome subunit beta type-1(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550641(CHEMBL4781914)
Affinity DataIC50: 320nMAssay Description:Inhibition of human 20S constitutive proteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550641(CHEMBL4781914)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 20S constitutive proteasome beta 2 subunit trypsin-like activity using fluorogenic peptide Ac-WLR-AMC as substrate in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550641(CHEMBL4781914)
Affinity DataIC50: 97nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550641(CHEMBL4781914)
Affinity DataIC50: 13nMAssay Description:Inhibition of human 20S immunoproteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence of PA2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550641(CHEMBL4781914)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta 2 subunit trypsin-like activity using fluorogenic peptide Ac-WLR-AMC as substrate in presence of PA28al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50550641(CHEMBL4781914)
Affinity DataIC50: 63nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed