BDBM50550530 CHEMBL4791796

SMILES Clc1ccc(CCN2CCN(CC2)c2ccccc2-c2cc(C(=O)NCCCN3CCCC3)c3cn[nH]c3n2)cc1Cl

InChI Key InChIKey=UYKVPOQVUKTFDL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550530   

TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550530(CHEMBL4791796)
Affinity DataIC50: 65nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550530(CHEMBL4791796)
Affinity DataEC50:  549nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in in human U2OS cells assessed as reduction in monomethylated p53 levels incubated for 24 hrs by immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed