BDBM50550519 CHEMBL4755178

SMILES O=C(NCCCN1CCCC1)c1cc(cc(c1)-c1ccccc1N1CCN(CCc2c[nH]c3ccccc23)CC1)C#N

InChI Key InChIKey=YOQNKQZUYYPRKE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50550519   

TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550519(CHEMBL4755178)
Affinity DataIC50: 28nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550519(CHEMBL4755178)
Affinity DataEC50:  270nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in in human U2OS cells assessed as reduction in monomethylated p53 levels incubated for 24 hrs by immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550519(CHEMBL4755178)
Affinity DataIC50: 27nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed