BDBM50550517 CHEMBL4792378

SMILES Cc1cccc(CCN2CCN(CC2)c2ccccc2-c2cc(cc(c2)C(=O)NCCCN2CCCC2)C#N)c1

InChI Key InChIKey=NERBFWPZZNGFFV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550517   

TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550517(CHEMBL4792378)
Affinity DataIC50: 31nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550517(CHEMBL4792378)
Affinity DataEC50:  1.21E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in in human U2OS cells assessed as reduction in monomethylated p53 levels incubated for 24 hrs by immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed