BDBM50550053 CHEMBL4779731

SMILES COc1ccccc1NC(=O)CC1SCCNC1=O

InChI Key InChIKey=REOXVRQZJMCZKK-UHFFFAOYSA-N

Data  2 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550053   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50550053(CHEMBL4779731)Copy SMILESCopy InChI

Affinity DataKd:  2.37E+5nMAssay Description:Binding affinity to full length biotinylated 6His/Avi-tagged/Tev-fused human MEK1 expressed in Escherichia coli in absence of AMP-PNP by SPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50550053(CHEMBL4779731)Copy SMILESCopy InChI

Affinity DataKd:  1.60E+5nMAssay Description:Binding affinity to full length biotinylated 6His/Avi-tagged/Tev-fused human MEK1 expressed in Escherichia coli in presence of AMP-PNP by SPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL