BDBM50550046 CHEMBL4789122

SMILES O=c1[nH]ccc2nc(cn12)-c1ccccc1

InChI Key InChIKey=TZYYQMDXTHSYMO-UHFFFAOYSA-N

Data  2 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550046   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50550046(CHEMBL4789122)Copy SMILESCopy InChI

Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to full length biotinylated 6His/Avi-tagged/Tev-fused human MEK1 expressed in Escherichia coli in absence of AMP-PNP by SPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50550046(CHEMBL4789122)Copy SMILESCopy InChI

Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to full length biotinylated 6His/Avi-tagged/Tev-fused human MEK1 expressed in Escherichia coli in presence of AMP-PNP by SPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL