BDBM50549737 CHEMBL4745518

SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCN(CCO)CC4)c(F)c3)nc2n1C12CC(C1)C2

InChI Key InChIKey=QOUGGDPQABJLGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549737   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549737(CHEMBL4745518)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549737(CHEMBL4745518)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human full-length GST-tagged CDK4/cyclinD1 expressed in baculovirus expression system using PEP as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed