BDBM50549735 CHEMBL4796706

SMILES CN(C)CCOc1ccc(Nc2ncc3c(C)c(C(C)=O)c(=O)n(C4CCCC4)c3n2)cc1F

InChI Key InChIKey=GBVXPZRKGCHAIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549735   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549735(CHEMBL4796706)
Affinity DataIC50: 32nMAssay Description:Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549735(CHEMBL4796706)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full-length GST-tagged CDK4/cyclinD1 expressed in baculovirus expression system using PEP as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549735(CHEMBL4796706)
Affinity DataIC50: 10nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/cyclinD3 (1 to 292 residues) expressed in baculovirus expression syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed