BDBM50549731 CHEMBL4796549

SMILES CC(C)N1CCN(CC1)c1ccc(Nc2ncc3CC4(CC(=O)NC4=O)N(C4CCCC4)c3n2)cc1

InChI Key InChIKey=WDVONLZSOJVUBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549731   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549731(CHEMBL4796549)
Affinity DataIC50: 71nMAssay Description:Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549731(CHEMBL4796549)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human full-length GST-tagged CDK4/cyclinD1 expressed in baculovirus expression system using PEP as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed