BDBM50549652 CHEMBL4757244

SMILES FC(F)(F)c1nccc(C2CCN(CC2)C(=O)C(=O)Nc2ccc(Cl)cn2)c1Cl

InChI Key InChIKey=UJDOVTBKENFSPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549652   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549652(CHEMBL4757244)
Affinity DataIC50: 301nMAssay Description:Inhibition of IDO1 in human SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549652(CHEMBL4757244)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TDO in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed