BDBM50549642 CHEMBL4781703

SMILES FC(F)c1ccc2c(OCC22CCN(CC2)C(=O)C(=O)Nc2ccc(Cl)cc2)c1

InChI Key InChIKey=GIBXJIHWLGMCBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549642   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549642(CHEMBL4781703)
Affinity DataIC50: 30nMAssay Description:Inhibition of IDO1 in human SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549642(CHEMBL4781703)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TDO in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed