BDBM50549604 CHEMBL4744398

SMILES [H][C@]1(CCCN1C)[C@@]1([H])COc2cc(ccc2O1)[N+]([O-])=O

InChI Key InChIKey=RGJUMUZTONCAMS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549604   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50549604(CHEMBL4744398)
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 transfected in HEK293 cell membranes preincubated for 5 mins followed by [3H]-epibatidine add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50549604(CHEMBL4744398)
Affinity DataKi:  1.35E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50549604(CHEMBL4744398)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-Epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane preincubated for 5 mins followed by [3H]-Epibatidine addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed