BDBM50549558 CHEMBL4755330

SMILES Cc1ccc(OCC(=O)NNC(=O)\C=C\c2ccc(O)c(O)c2)c(C)c1

InChI Key InChIKey=HDDOIBNGXAOLEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549558   

TargetProstaglandin G/H synthase 1(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50549558(CHEMBL4755330)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of COX-1 (unknown origin) assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50549558(CHEMBL4755330)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed