BDBM50549545 CHEMBL4743724

SMILES [H][C@@]1(CC[C@@]2(COc3ncc(cc23)C(F)(F)F)CC1)[C@H](C)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=LARQRQRFGGPTHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549545   

TargetTryptophan 2,3-dioxygenase(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549545(CHEMBL4743724)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of TDO in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549545(CHEMBL4743724)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of IDO1 in human SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed