BDBM50549536 CHEMBL4751227

SMILES CC[C@H](N1CCC2(COc3cc(ccc23)C(F)(F)F)CC1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=LJAQRRJZQKXEBX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50549536   

TargetCytochrome P450 2C9(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549536(CHEMBL4751227)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549536(CHEMBL4751227)
Affinity DataIC50: 38nMAssay Description:Inhibition of mouse IDO1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549536(CHEMBL4751227)
Affinity DataIC50: 360nMAssay Description:Inhibition of IDO1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549536(CHEMBL4751227)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of TDO in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549536(CHEMBL4751227)
Affinity DataIC50: 12nMAssay Description:Inhibition of IDO1 in human SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed