BDBM50549218 CHEMBL4787650

SMILES COc1ccc(NC(=O)C2CCN(CC2)C(=O)N[C@@H](CCC(=O)NC(C)(C)C)C(=O)N[C@@H](CCc2ccccc2)C(=O)NCc2ccccc2Cl)cc1

InChI Key InChIKey=CPLWQMIMLIPHCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549218   

TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50549218(CHEMBL4787650)
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed