BDBM50549217 CHEMBL4759432

SMILES CC(C)(C)NC(=O)CC[C@H](NC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)C#N)C(=O)N[C@@H](CCc1ccccc1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=PKXQGQZQLRURJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549217   

TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50549217(CHEMBL4759432)
Affinity DataIC50: 24nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed