BDBM50549201 CHEMBL4757494

SMILES CC(C)(C)CNC(=O)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)N1CCC(CC1)C(=O)Nc1cnccn1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=VUGZZPSHDUUUGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549201   

TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50549201(CHEMBL4757494)
Affinity DataIC50: 42nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed