BDBM50549019 CHEMBL4753808

SMILES C[C@H]1CN(CC[C@H]2CC[C@@H](CC2)N2C(=O)CC3(CCCC3)CC2=O)CCc2ccc(Cl)cc12

InChI Key InChIKey=DTQQYFXMBRLANH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50549019   

TargetD(3) dopamine receptor(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50549019(CHEMBL4753808)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50549019(CHEMBL4753808)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]OH-DPAT from recombinant human 5-HT1A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50549019(CHEMBL4753808)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-spiperone from recombinant human D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50549019(CHEMBL4753808)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]ketanserin from recombinant human 5-HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50549019(CHEMBL4753808)
Affinity DataKi:  293nMAssay Description:Displacement of [3H]-pyrilamine from human H1 histamine receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed