BDBM50548566 CHEMBL4796321

SMILES COc1ccc(-c2cccc(c2)C(C)=O)n2nc(nc12)C1CC1

InChI Key InChIKey=RKXZIARGENBWKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548566   

LigandPNGBDBM50548566(CHEMBL4796321)
Affinity DataIC50: 8nMAssay Description:Inhibition of human PDE4D catalytic domain using cAMP and FAM-conjugated cAMP by IMAP FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548566(CHEMBL4796321)
Affinity DataIC50: 24nMAssay Description:Inhibition of PDE4D in human PBMC assessed as reduction in lipopolysaccharide-induced TNFalpha production pre-incubated for 30 mins before LPS stimul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed