BDBM50548553 CHEMBL4795054

SMILES COC(=O)c1cccc(c1)-c1ccc(OC)c2nc(nn12)C1(CC1)C(=O)NCC(C)C

InChI Key InChIKey=DUKDVFIIAMEFSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548553   

LigandPNGBDBM50548553(CHEMBL4795054)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human PDE4D catalytic domain using cAMP and FAM-conjugated cAMP by IMAP FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548553(CHEMBL4795054)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE4D in human PBMC assessed as reduction in lipopolysaccharide-induced TNFalpha production pre-incubated for 30 mins before LPS stimul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed