BDBM50548196 CHEMBL4753188

SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2ccc(nc12)-c1cccc(F)c1

InChI Key InChIKey=SBMRKNIYXGMRRJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548196   

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Biogen

Curated by ChEMBL

LigandBDBM50548196(CHEMBL4753188)Copy SMILESCopy InChI

Affinity DataIC50: 490nMAssay Description:Inhibition of GLK (unknown origin) transfected in human 293T cells co-transfected with GFP-fused PKCtheta assessed as reduction in PKCtheta phosphory...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Biogen

Curated by ChEMBL

LigandBDBM50548196(CHEMBL4753188)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of GLK (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL