BDBM50548195 CHEMBL4782885

SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2cc(oc12)-c1cccc(F)c1

InChI Key InChIKey=DXBIXZHJSGDDFT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548195   

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Biogen

Curated by ChEMBL

LigandBDBM50548195(CHEMBL4782885)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GLK (unknown origin) transfected in human 293T cells co-transfected with GFP-fused PKCtheta assessed as reduction in PKCtheta phosphory...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Biogen

Curated by ChEMBL

LigandBDBM50548195(CHEMBL4782885)Copy SMILESCopy InChI

Affinity DataIC50: 18nMAssay Description:Inhibition of GLK (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL