BDBM50548177 CHEMBL4791952

SMILES COc1cc2nc(nc(NCCCNC(=O)C=C)c2cc1OC)N1CCCC1

InChI Key InChIKey=QTHRXIUTSUVNPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548177   

TargetN-lysine methyltransferase KMT5A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50548177(CHEMBL4791952)
Affinity DataIC50: 804nMAssay Description:Inhibition of recombinant SETD8 catalytic domain (unknown origin) (232 to 393 residues) expressed in Escherichia coli assessed as reduction in incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50548177(CHEMBL4791952)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant SETD8 catalytic domain (unknown origin) (232 to 393 residues) expressed in Escherichia coli assessed as reduction in incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed