BDBM50548148 CHEMBL4782173

SMILES Cc1nc2ccc(C)cn2c1-c1cc[nH]n1

InChI Key InChIKey=FLABUTFVIDAMFH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548148   

TargetLanosterol synthase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50548148(CHEMBL4782173)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of recombinant wild-type human COMT expressed in Escherichia coli BL21 using 4-nitrocatechol-Alexa488 as substrate in presence of cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50548148(CHEMBL4782173)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to human wild-type SUMO-tagged catechol O-methyltransferase assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed