BDBM50548112 CHEMBL4791612

SMILES Nc1nc(-c2ccccc2)c2ccccc2n1

InChI Key InChIKey=TXPOSODBCCBORG-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548112   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50548112(CHEMBL4791612)Copy SMILESCopy InChI

Affinity DataIC50: 21nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
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TargetAdenosine receptor A2a(Human)
Univ. Lille

Curated by ChEMBL

LigandBDBM50548112(CHEMBL4791612)Copy SMILESCopy InChI

Affinity DataKi:  198nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membrane incubated for 1 hr by microplate beta scintillation ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL