BDBM50548076 CHEMBL4781133::US11583532, Example 5.1

SMILES Cc1nc2ncnn2c(N)c1Cc1ccc(Br)c(OC(F)F)n1

InChI Key InChIKey=AZHBLVQIWNQJLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548076   

TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548076(CHEMBL4781133 | US11583532, Example 5.1)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548076(CHEMBL4781133 | US11583532, Example 5.1)
Affinity DataIC50: 0.130nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent