BDBM50547922 CHEMBL4761578

SMILES COc1cc(OC(F)(F)F)ccc1Oc1ccc(c(Br)c1C(=O)Nc1ccnc(c1)C(N)=O)C(F)(F)F

InChI Key InChIKey=JHJCGKNBSQFFOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547922   

TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547922(CHEMBL4761578 | US12441703, Compound 194)
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547922(CHEMBL4761578 | US12441703, Compound 194)
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent