BDBM50547749 CHEMBL4744480

SMILES CNC(=O)C[C@H]1O[C@@](C)(C(=O)OC)n2c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n1c4c23

InChI Key InChIKey=DNXFAQOLPLWSJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547749   

TargetProtein kinase C theta type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50547749(CHEMBL4744480)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50547749(CHEMBL4744480)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed