BDBM50547658 CHEMBL4744605

SMILES OC(=O)CN1CC(=O)Oc2c(\C=C\c3ccc(cc3)C(F)(F)F)cccc12

InChI Key InChIKey=HARGMXVTTDKSME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547658   

TargetAldo-keto reductase family 1 member B7(Rat)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50547658(CHEMBL4744605)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of rat kidney ALR1 using sodium D-glucuronate as substrate preincubated for 4 mins at 37 degC followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50547658(CHEMBL4744605)
Affinity DataIC50: 138nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins at 30 degC followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed