BDBM50547635 CHEMBL4798433

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)C#CC#Cc1c(C)cc(cc1-c1ccccc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=YCKBHJLGYBDIMU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50547635   

TargetNonstructural protein 5A(Hepacivirus C)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547635(CHEMBL4798433)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of HCV genotype 5a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547635(CHEMBL4798433)
Affinity DataIC50: 0.364nMAssay Description:Inhibition of HCV genotype 3a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547635(CHEMBL4798433)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of HCV genotype 4a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547635(CHEMBL4798433)
Affinity DataIC50: 0.0370nMAssay Description:Inhibition of HCV genotype 1a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547635(CHEMBL4798433)
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of HCV genotype 1b NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by Celltiter Glo a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547635(CHEMBL4798433)
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of HCV genotype 2a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed