BDBM50547418 CHEMBL4740085

SMILES COC(=O)N(C)c1c(N)nc(nc1N)-n1nc(Cc2cc(F)cc(F)c2F)c2ccccc12

InChI Key InChIKey=XGTWWTSGIOGZTH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547418   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50547418(CHEMBL4740085)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Merck

Curated by ChEMBL

LigandBDBM50547418(CHEMBL4740085)Copy SMILESCopy InChI

Affinity DataEC50:  110nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL