BDBM50547364 CHEMBL4778430

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)NCCc1ccccn1)-c1ccccc1

InChI Key InChIKey=CZDWSTNONBAKEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547364   

TargetCytochrome P450 3A4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50547364(CHEMBL4778430)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins in presence of NADPH generating system by LC-MS/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50547364(CHEMBL4778430)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human FPR expressed in human Chem-1 cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed