BDBM50547346 CHEMBL3741215

SMILES Cc1ccc2occ(CN3CCN(Cc4cn(-c5cccc(c5)C(F)(F)F)c5ccccc45)CC3)c(=O)c2c1

InChI Key InChIKey=IZDAKKZWUYYSLJ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547346   

TargetTumor necrosis factor ligand superfamily member 11(Human)
Agricultural University of Athens

Curated by ChEMBL
LigandPNGBDBM50547346(CHEMBL3741215)
Affinity DataKd: >1.10E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed